Both Lipitor and Crestor are excellent medications to help improve high cholesterol and to decrease your risk of heart attacks and strokes. In studies, Crestor was more effective at lowering total cholesterol levels and raising HDL levels (Jones, 2003).
Which is more effective atorvastatin or rosuvastatin?
Rosuvastatin (10 mg and 20 mg) was the most effective at reducing LDL-C (29.03% and 29.3%, resp.). Atorvastatin reduced LDL-C the most at a dose of 40 mg (22.8%), and pravastatin reduced LDL-C the most at a dose of 20 mg (20.3%). Moreover, rosuvastatin (10 mg) reduced triglycerides the most (−25.1%, ).
Can I switch from atorvastatin to rosuvastatin?
Conclusion: Switching from 10mg atorvastatin to 5mg rosuvastatin may be a useful therapeutic option to reduce sd LDL-C levels in Japanese hypercholesterolemic patients with T2DM.
Which is the best statin to take?
“By using non-HDL-C as a primary measure, we found that the three statins – Rosuvastatin, Simvastatin and Atorvastatin – were ranked most effective in the meta-analysis.”
What is the best statin with the least side effects?
According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.
Which has less side effects atorvastatin or rosuvastatin?
There were no significant differences between rosuvastatin and atorvastatin at any dose ratio for adverse events.
Is Crestor the best statin?
Crestor is made by AstraZeneca and is considered the most potent (strongest) statin. Like other statins, Crestor lowers total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol.
What is the most common side effect of Crestor?
The most common side effects may include:
Headache, muscle aches and pains, abdominal pain, weakness, and nausea. Additional side effects that have been reported with CRESTOR include memory loss and confusion.
Why was Crestor taken off the market?
Bayer withdrew cerivastatin in August, 2001, after the occurrence of unexpected cases of fatal rhabdomyolysis. The 80 mg dose of rosuvastatin was withdrawn by AstraZeneca because of safety concerns.
Is Crestor better tolerated than Lipitor?
Is Crestor safer than Lipitor? Crestor and Lipitor are both well tolerated. Any drug has side effects, with some rare but serious potential side effects, too. Studies (see above section) have shown that both medicines were tolerated well in trials.
What are the dangers of taking Crestor?
Common Crestor side effects may include headaches, abdominal pain and nausea. Skeletal muscle effects, such as myopathy and rhabdomyolysis, are among the serious Crestor side effects.
Common Side Effects of Crestor
- Headache.
- Muscle aches and pains.
- Abdominal pain.
- Weakness.
- Nausea.
- Memory loss and confusion.
What is the downside of atorvastatin?
Cons. Statins such as atorvastatin (Lipitor) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
What is the safest statin for elderly?
Atorvastatin or fluvastatin are usually recommended because there is no need to adjust the dose according to the glomerular filtration rate [28]. In patients without diagnosed atherosclerotic cardiovascular disease, it is indicated a moderate dose of statin, such as atorvastatin 20 mg daily [28].
What is the most serious side effect of atorvastatin?
Serious side effects
you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and kidney damage.
What is the first drug of choice for cholesterol?
As with people who already have known CVD, when the decision is made to start medication, the first choice is usually a statin. (See ‘Statins’ below.) People with high triglyceride levels — Triglycerides, like cholesterol, are a type of lipid.
What is the most prescribed statin?
Most popular prescriptions. Atorvastatin (Lipitor) is a statin used to treat high cholesterol.
Which is the best statin to take for cholesterol?
Rosuvastatin and atorvastatin are the best at lowering LDL cholesterol.
Which cholesterol medication is the safest?
Still, all in all, the statins are the safest and best tolerated of all cholesterol-lowering medications.
What is the best substitute for atorvastatin?
- Other alternatives to atorvastatin.
- Other HMG CoA Reductase Inhibitors (statins) such as: Crestor (rosuvastatin), Zocor (simvastatin), Pravachol (pravastatin), or Mevachor (lovastatin)
- Colestid (colestipol)
- Tricor (fenofibrate)
- Zetia (ezetimibe)
- WelChol (colesevelam)
Is Crestor hard on your liver?
Liver disease: Liver disease can also be a severe side effect of Crestor. Your doctor should do blood tests to check your liver before you start taking Crestor. They should also do these tests if you have symptoms of liver disease while you take the drug.
Does Crestor make you gain weight?
Crestor does not appear to cause weight gain directly, but it may indirectly lead to increased weight. Crestor’s most common side effects in clinical trials include headaches, nausea, myalgia (muscle pain), asthenia (weakness or lack of energy), and constipation (FDA, 2010).