Bitter orange is currently considered safe to eat and may offer some health benefits, but if you have high blood pressure or are at high risk of heart attack or stroke, you should ask your doctor before eating it.
What are the side effects of synephrine?
Common side effects of Neo-Synephrine include:
- burning,
- stinging,
- pain,
- increased redness of the eye,
- tearing or blurred vision,
- headache,
- tremor,
- nausea,
What are the side effects of bitter orange?
Bitter orange, taken by itself or with stimulants such as caffeine or caffeine-containing herbs, might increase the risk for high blood pressure, fainting, heart attack, stroke, and other serious side effects. There are also reports that bitter orange can trigger headaches in some people.
How much bitter orange is safe?
Dosage and safety information
Generally, bitter orange extracts in dietary supplements are safe to consume in doses of 50–98 mg per day ( 1 , 23 ). One study showed that 40 mg of synephrine combined with 320 mg of caffeine is a safe dose of these combined ingredients ( 3 ).
Is it OK to drink bitter orange juice?
Bitter orange juice is considered as safe to drink as any other citrus fruit juice (as long as it is not consumed in excess).
How much synephrine is in bitter orange?
The bitter orange extract contained 6% p‐synephrine, and therefore, the dosing was 0.34‐mg p‐synephrine/kg.
How long does synephrine HCL stay in your system?
Several studies have shown that the half-life of p-synephrine is between 2 and 3 hours.
Does bitter orange raise blood pressure?
Due to the similarity in chemical structure to ephedrine and the potential sympathomimetic effects of synephrine, it is hypothesized that bitter orange may increase blood pressure (BP) and heart rate (HR).
Can you eat a trifoliate orange?
TRIFOLIATE ORANGE FACTS
It is a large, deciduous shrub that produces an unusually sour, downy fruit considered to be nearly inedible when raw but medicinally beneficial and delicious when cooked. The fruit is commonly juiced, made into marmalades, jams, jellies, or candied.
Is bitter orange banned by the FDA?
Bitter orange contains synephrine, which is similar to ephedra — a chemical the FDA banned because it raises blood pressure and was linked to heart attacks and stroke.
Does bitter orange help with weight loss?
Although historically used to stimulate appetite, bitter orange is frequently found in modern weight-loss formulas because synephrine is similar to the compound ephedrine, which is known to promote weight loss.
How much weight can you lose with synephrine?
And when you review the literature, you find a wide variety of dosages of synephrine used for weight loss purposes. The most effective dosages were in the range of 25 to 50 milligrams per day, though, with 50 milligrams significantly outperforming 25 milligrams.
What is similar to ephedrine?
Other ephedra alternatives: Green tea extract. Green tea typically contains less caffeine per cup than coffee, plus many antioxidant vitamins. Caffeine itself can be a mild appetite suppressant, and proponents say there may be other substances in green tea that could slightly speed calorie burning.
Why did my orange juice turn bitter?
Ever wonder why your fresh squeezed navel orange juice tastes bitter after its been sitting around for a little bit? Blame limonin. Limonin is a bitter compound found in most citrus but especially in navels oranges that increases in concentration the longer it sits.
What does bitter orange look like?
Bitter oranges are small fruits, usually measuring about 3 inches in diameter and weighing 5 to 6 ounces. Their skin is rough and dimpled, with a thick rind and yellow-orange color.
How do you get rid of bitterness in orange juice?
The major scientific methods used for the reduction of bitterness in the citrus fruit juices are lye treatment, addition of sugars, β-cyclodextrin, hot water treatment, cellulose acetate layers, enzymatic methods using microbial consortia.
Does synephrine fail drug test?
Synephrine and drug testing
Synephrine (and octopamine) will not cause a positive result on the confirmation drug tests. However, octopamine will show up if a steroid test is conducted. The National Collegiate Athletic Association (NCAA) bans both synephrine and octopamine.
Is bitter orange good for you?
Bitter orange has been used in traditional Chinese medicine for indigestion, nausea, and constipation. Today, various bitter orange products are promoted for heartburn, nasal congestion, weight loss, appetite stimulation or suppression, and athletic performance.
Is synephrine the same as ephedrine?
The main differences of the synephrine isomers compared for example to the ephedrines are the hydroxy-substitutions on the benzene ring. Synephrines are direct sympathomimetic drugs while the ephedrines are both direct and indirect sympathomimetics.
What foods contain synephrine?
P-synephrine, a substance found in the skin of bitter oranges (Citrus aurantium ssp. aurantium), is also found in other species of Citrus. P-synephrine, as well as other ingredients obtained from Citrus spp. fruits, is used in many food supplements which allegedly reduce body fat or can modify body composition.
Does synephrine help with weight loss?
Synephrine is a stimulant similar to caffeine so it can help burn fat, suppress appetite, and increase energy. It’s often taken as a weight management supplement to boost metabolism and reduce fat. Synephrine can be taken with caffeine to optimize fat burning.